Calcium-driven regulation of voltage-sensing domains in BK channels

Allosteric interactions between the voltage-sensing domain (VSD), the Ca(2+)-binding sites, and the pore domain govern the mammalian Ca(2+)- and voltage-activated K(+) (BK) channel opening. However, the functional relevance of the crosstalk between the Ca(2+)- and voltage-sensing mechanisms on BK ch...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Lorenzo-Ceballos, Yenisleidy, Carrasquel-Ursulaez, Willy, Castillo, Karen, Alvarez, Osvaldo, Latorre, Ramon
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2019
Fag:
Structural Biology and Molecular Biophysics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763263/
https://ncbi.nlm.nih.gov/pubmed/31509109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44934
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