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Determination of the Stoichiometry between α- and γ1 Subunits of the BK Channel Using LRET

Two families of accessory proteins, β and γ, modulate BK channel gating and pharmacology. Notably, in the absence of internal Ca(2+), the γ1 subunit promotes a large shift of the BK conductance-voltage curve to more negative potentials. However, very little is known about how α- and γ1 subunits inte...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Carrasquel-Ursulaez, Willy, Alvarez, Osvaldo, Bezanilla, Francisco, Latorre, Ramon
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129150/
https://ncbi.nlm.nih.gov/pubmed/29705199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.04.008
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