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The molecular nature of the 17β-Estradiol binding site in the voltage- and Ca(2+)-activated K(+) (BK) channel β1 subunit
The accessory β1 subunit modulates the Ca(2+)- and voltage-activated K(+) (BK) channel gating properties mainly by increasing its apparent Ca(2+) sensitivity. β1 plays an important role in the modulation of arterial tone and blood pressure by vascular smooth muscle cells (SMCs). 17β-estradiol (E2) i...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6620312/ https://ncbi.nlm.nih.gov/pubmed/31292456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45942-1 |
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