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Rapid, Quantitative Therapeutic Screening for Alzheimer’s Enzymes Enabled by Optimal Signal Transduction with Transistors
We show that commercially sourced n-channel silicon field-effect transistors (nFETs) operating above their threshold voltage with closed loop feedback to maintain a constant channel current allow a pH readout resolution of (7.2±0.3)×10(−3) at a bandwidth of 10 Hz, or ≈3-fold better than the open loo...
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| Publicado no: | Analyst |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7443690/ https://ncbi.nlm.nih.gov/pubmed/32159165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9an01804b |
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