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Microsecond-timescale simulations suggest 5-HT–mediated preactivation of the 5-HT(3A) serotonin receptor
Aided by efforts to improve their speed and efficiency, molecular dynamics (MD) simulations provide an increasingly powerful tool to study the structure–function relationship of pentameric ligand-gated ion channels (pLGICs). However, accurate reporting of the channel state and observation of alloste...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6955379/ https://ncbi.nlm.nih.gov/pubmed/31871207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1908848117 |
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