Protein phosphatase 4 promotes Hedgehog signaling through dephosphorylation of Suppressor of fused

Reversible phosphorylation of Suppressor of fused (Sufu) is essential for Sonic Hedgehog (Shh) signal transduction. Sufu is stabilized under dual phosphorylation of protein kinase A (PKA) and glycogen synthase kinase 3β (GSK3β). Its phosphorylation is reduced with the activation of Shh signaling. Ho...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Liao, Hengqing, Cai, Jing, Liu, Chen, Shen, Longyan, Pu, Xiaohong, Yao, Yixing, Han, Bo’ang, Yu, Tingting, Cheng, Steven Y., Yue, Shen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7442787/
https://ncbi.nlm.nih.gov/pubmed/32826873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02843-w
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi