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Hedgehog signaling downregulates Suppressor of Fused through the HIB/SPOP-Crn axis in Drosophila

Hedgehog (Hh) signaling plays vital roles in animal development and tissue homeostasis, and its misregulation causes congenital diseases and several types of cancer. Suppressor of Fused (Su(fu)) is a conserved inhibitory component of the Hh signaling pathway, but how it is regulated remains poorly u...

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Bibliografski detalji
Glavni autori: Liu, Chen, Zhou, Zizhang, Yao, Xia, Chen, Ping, Sun, Man, Su, Miya, Chang, Cunjie, Yan, Jun, Jiang, Jin, Zhang, Qing
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011344/
https://ncbi.nlm.nih.gov/pubmed/24603360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.29
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