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Hedgehog signaling downregulates Suppressor of Fused through the HIB/SPOP-Crn axis in Drosophila
Hedgehog (Hh) signaling plays vital roles in animal development and tissue homeostasis, and its misregulation causes congenital diseases and several types of cancer. Suppressor of Fused (Su(fu)) is a conserved inhibitory component of the Hh signaling pathway, but how it is regulated remains poorly u...
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| Glavni autori: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4011344/ https://ncbi.nlm.nih.gov/pubmed/24603360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.29 |
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