Hedgehog signaling downregulates Suppressor of Fused through the HIB/SPOP-Crn axis in Drosophila

Hedgehog (Hh) signaling plays vital roles in animal development and tissue homeostasis, and its misregulation causes congenital diseases and several types of cancer. Suppressor of Fused (Su(fu)) is a conserved inhibitory component of the Hh signaling pathway, but how it is regulated remains poorly u...

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Detalhes bibliográficos
Main Authors: Liu, Chen, Zhou, Zizhang, Yao, Xia, Chen, Ping, Sun, Man, Su, Miya, Chang, Cunjie, Yan, Jun, Jiang, Jin, Zhang, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011344/
https://ncbi.nlm.nih.gov/pubmed/24603360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.29
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