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Protein phosphatase 4 promotes Hedgehog signaling through dephosphorylation of Suppressor of fused
Reversible phosphorylation of Suppressor of fused (Sufu) is essential for Sonic Hedgehog (Shh) signal transduction. Sufu is stabilized under dual phosphorylation of protein kinase A (PKA) and glycogen synthase kinase 3β (GSK3β). Its phosphorylation is reduced with the activation of Shh signaling. Ho...
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| Publicado no: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7442787/ https://ncbi.nlm.nih.gov/pubmed/32826873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02843-w |
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