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Targeting MCL-1 in Hematologic Malignancies: Rationale and Progress
Myeloid cell leukemia sequence 1 (MCL-1) is an antiapoptotic protein that plays a key role in promoting cell survival in multiple myeloma (MM), acute myeloid leukemia (AML), and non-Hodgkin lymphoma (NHL). Overexpression of MCL-1 is associated with treatment resistance and poor prognosis; thus, MCL-...
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| Publicat a: | Blood Rev |
|---|---|
| Autors principals: | , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7442684/ https://ncbi.nlm.nih.gov/pubmed/32204955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.blre.2020.100672 |
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