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mTORC1 pathway is involved in the kappa opioid receptor activation-induced increase in excessive alcohol drinking in mice
KOP-r agonist U50,488H produces strong aversion and anxiety/depression-like behaviors that enhance alcohol intake and promote alcohol seeking and relapse-like drinking in rodents. Mammalian target of rapamycin complex 1 (mTORC1) pathway in mouse striatum is highly involved in excessive alcohol intak...
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| Vydáno v: | Pharmacol Biochem Behav |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7442164/ https://ncbi.nlm.nih.gov/pubmed/32470351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2020.172954 |
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