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mTORC1 pathway is involved in the kappa opioid receptor activation-induced increase in excessive alcohol drinking in mice
KOP-r agonist U50,488H produces strong aversion and anxiety/depression-like behaviors that enhance alcohol intake and promote alcohol seeking and relapse-like drinking in rodents. Mammalian target of rapamycin complex 1 (mTORC1) pathway in mouse striatum is highly involved in excessive alcohol intak...
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| 發表在: | Pharmacol Biochem Behav |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7442164/ https://ncbi.nlm.nih.gov/pubmed/32470351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2020.172954 |
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