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Clinically utilized kappa-opioid receptor agonist nalfurafine combined with low-dose naltrexone prevents alcohol relapse-like drinking in male and female mice

Alcohol relapse is a treatment goal for alcohol dependence and the target for medications’ development. Clinically utilized nalfurafine (NFF) is a potent and selective kappa-opioid receptor (KOP-r) agonist, with fewer side effects (e.g., sedation or anhedonia) than classic KOP-r full agonists. We ha...

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Bibliografische gegevens
Gepubliceerd in:Brain Res
Hoofdauteurs: Zhou, Yan, Jeanne Kreek, Mary
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779526/
https://ncbi.nlm.nih.gov/pubmed/31469985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2019.146410
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