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Clinically utilized kappa-opioid receptor agonist nalfurafine combined with low-dose naltrexone prevents alcohol relapse-like drinking in male and female mice
Alcohol relapse is a treatment goal for alcohol dependence and the target for medications’ development. Clinically utilized nalfurafine (NFF) is a potent and selective kappa-opioid receptor (KOP-r) agonist, with fewer side effects (e.g., sedation or anhedonia) than classic KOP-r full agonists. We ha...
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| Опубликовано в: : | Brain Res |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6779526/ https://ncbi.nlm.nih.gov/pubmed/31469985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2019.146410 |
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