Synergistic blockade of alcohol escalation drinking in mice by a combination of novel kappa opioid receptor agonist Mesyl Salvinorin B and naltrexone

Mesyl Salvinorin B (MSB) is a potent selective kappa opioid receptor (KOP-r) agonist that has potential for development as an anti-psychostimulant agent with fewer side-effects (e.g., sedation, depression and dysphoria) than classic KOP-r agonists. However, no such study has been done on alcohol. We...

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Gepubliceerd in:Brain Res
Hoofdauteurs: Zhou, Yan, Cowley, Rachel Saylor, Ben, Konrad, Prisinzano, Thomas E, Kreek, Mary Jeanne
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398281/
https://ncbi.nlm.nih.gov/pubmed/28263712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2017.02.027
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