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Computer-aided screening for potential TMPRSS2 inhibitors: a combination of pharmacophore modeling, molecular docking and molecular dynamics simulation approaches

Transmembrane serine protease 2 (TMPRSS2) has been established as one of the host proteins that facilitate entry of coronaviruses into host cells. One of the approaches often employed towards preventing the entry and proliferation of viruses is computer-aided inhibition studies to identify potent co...

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Detalhes bibliográficos
Publicado no:J Biomol Struct Dyn
Main Authors: Idris, Mukhtar Oluwaseun, Yekeen, Abeeb Abiodun, Alakanse, Oluwaseun Suleiman, Durojaye, Olanrewaju Ayodeji
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7441808/
https://ncbi.nlm.nih.gov/pubmed/32672528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07391102.2020.1792346
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