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Computer-aided screening for potential TMPRSS2 inhibitors: a combination of pharmacophore modeling, molecular docking and molecular dynamics simulation approaches

Transmembrane serine protease 2 (TMPRSS2) has been established as one of the host proteins that facilitate entry of coronaviruses into host cells. One of the approaches often employed towards preventing the entry and proliferation of viruses is computer-aided inhibition studies to identify potent co...

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Podrobná bibliografie
Vydáno v:J Biomol Struct Dyn
Hlavní autoři: Idris, Mukhtar Oluwaseun, Yekeen, Abeeb Abiodun, Alakanse, Oluwaseun Suleiman, Durojaye, Olanrewaju Ayodeji
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7441808/
https://ncbi.nlm.nih.gov/pubmed/32672528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07391102.2020.1792346
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