Muc5ac Expression Protects the Colonic Barrier in Experimental Colitis

BACKGROUND: The mucus gel layer (MGL) lining the colon is integral to exclusion of bacteria and maintaining intestinal homeostasis in health and disease. Some MGL defects allowing bacteria to directly contact the colonic surface are commonly observed in ulcerative colitis (UC). The major macromolecu...

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Detalhes bibliográficos
Publicado no:Inflamm Bowel Dis
Main Authors: Olli, Kristine E, Rapp, Caroline, O’Connell, Lauren, Collins, Colm B, McNamee, Eoin N, Jensen, Owen, Jedlicka, Paul, Allison, Kristen C, Goldberg, Matthew S, Gerich, Mark E, Frank, Daniel N, Ir, Diana, Robertson, Charles E, Evans, Christopher M, Aherne, Carol M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Basic Science Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7441107/
https://ncbi.nlm.nih.gov/pubmed/32385500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ibd/izaa064
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