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Detrimental role of the airway mucin Muc5ac during ventilator-induced lung injury

Acute lung injury (ALI) is associated with high morbidity and mortality in critically ill patients. At present, the functional contribution of airway mucins to ALI is unknown. We hypothesized that excessive mucus production could be detrimental during lung injury. Initial transcriptional profiling o...

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Huvudupphovsmän: Koeppen, M, McNamee, EN, Brodsky, KS, Aherne, CM, Faigle, M, Downey, GP, Colgan, SP, Evans, CM, Schwartz, DA, Eltzschig, HK
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890100/
https://ncbi.nlm.nih.gov/pubmed/23187315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2012.114
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