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Alpha1-antitrypsin therapy ameliorates acute colitis and chronic murine ileitis

BACKGROUND: Fecal alpha-1-antitrypsin (AAT) clearance has been a marker of clinical disease severity in inflammatory bowel diseases (IBD) for many years. While AAT deficiency is more often associated with lung and liver pathologies, AAT-deficient patients with concomitant IBD have been shown to deve...

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Detalhes bibliográficos
Publicado no:Inflamm Bowel Dis
Main Authors: Collins, Colm B., Aherne, Carol M., Ehrentraut, Stefan F., Gerich, Mark E., McNamee, Eóin N., McManus, Martine C., Lebsack, Matthew D.P., Jedlicka, Paul, Azam, Tania, de Zoeten, Edwin F., Dinarello, Charles A., Rivera-Nieves, Jesús
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654462/
https://ncbi.nlm.nih.gov/pubmed/23835442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0b013e31829292aa
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