A social encounter drives gene expression changes linked to neuronal function, brain development, and related disorders in mice expressing the serotonin transporter Ala56 variant.

Multiple lines of evidence implicate the serotonin (5-HT) system in social function, including biomarker findings in autism spectrum disorder. In mice, knock-in of a rare Gly56Ala substitution in the serotonin transporter (SERT) causes elevated whole blood 5-HT levels, increased 5-HT clearance in th...

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Bibliografske podrobnosti
izdano v:Neurosci Lett
Main Authors: O’Reilly, Kally C., Anacker, Allison M. J., Rogers, Tiffany D., Forsberg, C. Gunnar, Wang, Jing, Zhang, Bing, Blakely, Randy D., Veenstra-VanderWeele, Jeremy
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7440397/
https://ncbi.nlm.nih.gov/pubmed/32437898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2020.135027
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