A social encounter drives gene expression changes linked to neuronal function, brain development, and related disorders in mice expressing the serotonin transporter Ala56 variant.

Multiple lines of evidence implicate the serotonin (5-HT) system in social function, including biomarker findings in autism spectrum disorder. In mice, knock-in of a rare Gly56Ala substitution in the serotonin transporter (SERT) causes elevated whole blood 5-HT levels, increased 5-HT clearance in th...

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Detaylı Bibliyografya
Yayımlandı:Neurosci Lett
Asıl Yazarlar: O’Reilly, Kally C., Anacker, Allison M. J., Rogers, Tiffany D., Forsberg, C. Gunnar, Wang, Jing, Zhang, Bing, Blakely, Randy D., Veenstra-VanderWeele, Jeremy
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7440397/
https://ncbi.nlm.nih.gov/pubmed/32437898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2020.135027
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