Modeling rare gene variation to gain insight into the oldest biomarker in autism: construction of the serotonin transporter Gly56Ala knock-in mouse

Alterations in peripheral and central indices of serotonin (5-hydroxytryptamine, 5-HT) production, storage and signaling have long been associated with autism. The 5-HT transporter gene (HTT, SERT, SLC6A4) has received considerable attention as a potential risk locus for autism-spectrum disorders, a...

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Detalhes bibliográficos
Main Authors: Veenstra-VanderWeele, Jeremy, Jessen, Tammy N., Thompson, Brent J., Carter, Michelle, Prasad, Harish C., Steiner, Jennifer A., Sutcliffe, James. S., Blakely, Randy D.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786076/
https://ncbi.nlm.nih.gov/pubmed/19960097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11689-009-9020-0
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