Integrin β3 Haploinsufficiency Modulates Serotonin Transport and Antidepressant-Sensitive Behavior in Mice

Converging lines of evidence have identified genetic interactions between the serotonin transporter (SERT) gene and ITGB3, which encodes the β3 subunit that forms the αIIbβ3 and αvβ3 integrin receptor complexes. Here we examine the consequences of haploinsufficiency in the mouse integrin β3 subunit...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Mazalouskas, Matthew, Jessen, Tammy, Varney, Seth, Sutcliffe, James S, Veenstra-VanderWeele, Jeremy, Cook, Edwin H, Carneiro, Ana M D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839525/
https://ncbi.nlm.nih.gov/pubmed/25684064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.51
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