MPC1 Deficiency Promotes CRC Liver Metastasis via Facilitating Nuclear Translocation of β-Catenin

Accumulating evidence has pointed out that metastasis is the leading cause of death in several malignant tumor, including CRC. During CRC, metastatic capacity is closely correlated with reprogrammed energy metabolism. Mitochondrial Pyruvate Carrier 1 (MPC1), as the carrier of transporting pyruvate i...

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Bibliografiske detaljer
Udgivet i:J Immunol Res
Main Authors: Tian, Guang-Ang, Xu, Chun-Jie, Zhou, Kai-Xia, Zhang, Zhi-Gang, Gu, Jian-Ren, Zhang, Xue-Li, Wang, Ya-Hui
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7439788/
https://ncbi.nlm.nih.gov/pubmed/32851100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8340329
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