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Nuclear translocation of beta-catenin in colorectal cancer
Post-translational stabilization of beta-catenin through mutation of the adenomatous polyposis coli (APC) gene has been proposed as an early step in colorectal carcinogenesis. Beta-catenin may translocate from the cytoplasm to the nucleus, where it might serve as a transcriptional factor to stimulat...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2000
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2374509/ https://ncbi.nlm.nih.gov/pubmed/10817505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.1112 |
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