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Nuclear translocation of beta-catenin in colorectal cancer

Post-translational stabilization of beta-catenin through mutation of the adenomatous polyposis coli (APC) gene has been proposed as an early step in colorectal carcinogenesis. Beta-catenin may translocate from the cytoplasm to the nucleus, where it might serve as a transcriptional factor to stimulat...

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Hlavní autoři: Kobayashi, M, Honma, T, Matsuda, Y, Suzuki, Y, Narisawa, R, Ajioka, Y, Asakura, H
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374509/
https://ncbi.nlm.nih.gov/pubmed/10817505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.1112
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