MPC1 Deficiency Promotes CRC Liver Metastasis via Facilitating Nuclear Translocation of β-Catenin

Accumulating evidence has pointed out that metastasis is the leading cause of death in several malignant tumor, including CRC. During CRC, metastatic capacity is closely correlated with reprogrammed energy metabolism. Mitochondrial Pyruvate Carrier 1 (MPC1), as the carrier of transporting pyruvate i...

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: Tian, Guang-Ang, Xu, Chun-Jie, Zhou, Kai-Xia, Zhang, Zhi-Gang, Gu, Jian-Ren, Zhang, Xue-Li, Wang, Ya-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7439788/
https://ncbi.nlm.nih.gov/pubmed/32851100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8340329
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