MPC1 Deficiency Promotes CRC Liver Metastasis via Facilitating Nuclear Translocation of β-Catenin

Accumulating evidence has pointed out that metastasis is the leading cause of death in several malignant tumor, including CRC. During CRC, metastatic capacity is closely correlated with reprogrammed energy metabolism. Mitochondrial Pyruvate Carrier 1 (MPC1), as the carrier of transporting pyruvate i...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Immunol Res
Auteurs principaux: Tian, Guang-Ang, Xu, Chun-Jie, Zhou, Kai-Xia, Zhang, Zhi-Gang, Gu, Jian-Ren, Zhang, Xue-Li, Wang, Ya-Hui
Format: Artigo
Langue:Inglês
Publié: Hindawi 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7439788/
https://ncbi.nlm.nih.gov/pubmed/32851100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8340329
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