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Nuclear-Cytoplasmic Shuttling of Menin Regulates Nuclear Translocation of β-Catenin
Menin, which is encoded by the multiple endocrine neoplasia type 1 (MEN1) gene, is a tumor suppressor and transcriptional regulator. Menin controls proliferation and apoptosis of cells, especially pancreatic β cells. We have found that menin contains two functional nuclear export signals and that th...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2756891/ https://ncbi.nlm.nih.gov/pubmed/19651895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00335-09 |
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