Nuclear-Cytoplasmic Shuttling of Menin Regulates Nuclear Translocation of β-Catenin

Menin, which is encoded by the multiple endocrine neoplasia type 1 (MEN1) gene, is a tumor suppressor and transcriptional regulator. Menin controls proliferation and apoptosis of cells, especially pancreatic β cells. We have found that menin contains two functional nuclear export signals and that th...

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Detalhes bibliográficos
Main Authors: Cao, Yanan, Liu, Ruixin, Jiang, Xiuli, Lu, Jieli, Jiang, Jingjing, Zhang, Changxian, Li, Xiaoying, Ning, Guang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756891/
https://ncbi.nlm.nih.gov/pubmed/19651895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00335-09
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