Targeting β-catenin signaling for therapeutic intervention in MEN1-deficient pancreatic neuroendocrine tumours

Inactivating MEN1 mutations are the most common genetic defects present in sporadic and inherited pancreatic neuroendocrine tumours (PNETs). The lack of interventional therapies prompts us to explore the therapeutic approach of targeting β-catenin signalling in MEN1-mutant PNETs. Here we show the ME...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Jiang, Xiuli, Cao, Yanan, Li, Feng, Su, Yutong, Li, Yanli, Peng, Ying, Cheng, Yulong, Zhang, Changxian, Wang, Weiqing, Ning, Guang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284642/
https://ncbi.nlm.nih.gov/pubmed/25517963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6809
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