Activation of PPARγ in Myeloid Cells Promotes Progression of Epithelial Lung Tumors through TGF- β1

Lung cancer is a heterogeneous disease in which patient-specific treatments are desirable and the development of targeted therapies has been effective. Though mutations in KRAS are frequent in lung adenocarcinoma, there are currently no targeted agents against KRAS. Using a mouse lung adenocarcinoma...

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Veröffentlicht in:Mol Cancer Res
Hauptverfasser: Sippel, Trisha R, Johnson, Amber M, Li, Howard Y, Hanson, Dwight, Nguyen, Teresa T, Bullock, Bonnie L, Poczobutt, Joanna M, Kwak, Jeff W, Kleczko, Emily K, Weiser-Evans, Mary C, Nemenoff, Raphael A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7439607/
https://ncbi.nlm.nih.gov/pubmed/31088909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-19-0236
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