Deletion of 5-Lipoxygenase in the Tumor Microenvironment Promotes Lung Cancer Progression and Metastasis through Regulating T Cell Recruitment

Eicosanoids, including PGs, produced by cyclooxygenases (COX), and leukotrienes, produced by 5-lipoxygenase (5-LO) have been implicated in cancer progression. These molecules are produced by both cancer cells and the tumor microenvironment (TME). We previously reported that both COX and 5-LO metabol...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Poczobutt, Joanna M., Nguyen, Teresa T., Hanson, Dwight, Li, Howard, Sippel, Trisha R., Weiser-Evans, Mary C. M., Gijon, Miguel, Murphy, Robert C., Nemenoff, Raphael A.
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2016
Assuntos:
Tumor Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705594/
https://ncbi.nlm.nih.gov/pubmed/26663781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501648
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