Activation of PPARγ in Myeloid Cells Promotes Progression of Epithelial Lung Tumors through TGF- β1

Lung cancer is a heterogeneous disease in which patient-specific treatments are desirable and the development of targeted therapies has been effective. Though mutations in KRAS are frequent in lung adenocarcinoma, there are currently no targeted agents against KRAS. Using a mouse lung adenocarcinoma...

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Udgivet i:Mol Cancer Res
Main Authors: Sippel, Trisha R, Johnson, Amber M, Li, Howard Y, Hanson, Dwight, Nguyen, Teresa T, Bullock, Bonnie L, Poczobutt, Joanna M, Kwak, Jeff W, Kleczko, Emily K, Weiser-Evans, Mary C, Nemenoff, Raphael A
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7439607/
https://ncbi.nlm.nih.gov/pubmed/31088909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-19-0236
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