PET, image-guided HDAC inhibition of pediatric diffuse midline glioma improves survival in murine models

Efforts at altering the dismal prognosis of pediatric midline gliomas focus on direct delivery strategies like convection-enhanced delivery (CED), where a cannula is implanted into tumor. Successful CED treatments require confirmation of tumor coverage, dosimetry, and longitudinal in vivo pharmacoki...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Tosi, Umberto, Kommidi, Harikrishna, Adeuyan, Oluwaseyi, Guo, Hua, Maachani, Uday Bhanu, Chen, Nandi, Su, Taojunfeng, Zhang, Guoan, Pisapia, David J., Dahmane, Nadia, Ting, Richard, Souweidane, Mark M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7439439/
https://ncbi.nlm.nih.gov/pubmed/32832670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb4105
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