EXTH-55. PET, IMAGE-GUIDED HDAC INHIBITION OF PEDIATRIC DIFFUSE MIDLINE GLIOMA IMPROVES SURVIVAL IN MURINE MODELS

Efforts at altering the dismal prognosis of pediatric midline gliomas focus on direct-delivery strategies like convection-enhanced delivery (CED), where a cannula is implanted into tumor. Successful CED treatments require confirmation of tumor coverage, dosimetry, and longitudinal in vivo pharmacoki...

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Vydáno v:Neuro Oncol
Hlavní autoři: Tosi, Umberto, Kommidi, Harikrishna, Adeuyan, Oluwaseyi, Guo, Hua, Maachani, Uday Bhanu, Chen, Nandi, Su, Taojunfeng, Zhang, Guoan, Pisapia, David, Dahmane, Nadia, Ting, Richard, Souweidane, Mark
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Preclinical Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651164/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.409
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