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Epigenetically heterogeneous tumor cells direct collective invasion through filopodia-driven fibronectin micropatterning
Tumor heterogeneity drives disease progression, treatment resistance, and patient relapse, yet remains largely underexplored in invasion and metastasis. Here, we investigated heterogeneity within collective cancer invasion by integrating DNA methylation and gene expression analysis in rare purified...
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| 出版年: | Sci Adv |
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| 主要な著者: | , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Association for the Advancement of Science
2020
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7439406/ https://ncbi.nlm.nih.gov/pubmed/32832657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz6197 |
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