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Prognostic significance of an invasive leader cell-derived mutation cluster on chromosome 16q

BACKGROUND: Intra-tumoral heterogeneity is defined by subpopulations with varying genotypes and phenotypes. Specialized, highly invasive leader cells and less invasive follower cells are phenotypically distinct subpopulations that cooperate during collective cancer invasion. Since leader cells are a...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer
Hauptverfasser: Pedro, Brian, Rupji, Manali, Dwivedi, Bhakti, Kowalski, Jeanne, Konen, Jessica M., Owonikoko, Taofeek K., Ramalingam, Suresh S., Vertino, Paula M., Marcus, Adam I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7275903/
https://ncbi.nlm.nih.gov/pubmed/32315457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.32903
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