Gut Metabolite TMAO Induces Synaptic Plasticity Deficits by Promoting Endoplasmic Reticulum Stress

Dysbiosis of gut microbiota is strongly associated with metabolic diseases including diabetes mellitus, obesity, and cardiovascular disease. Recent studies indicate that Trimethylamine N-oxide (TMAO), a gut microbe-dependent metabolite is implicated in the development of age-related cognitive declin...

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Detalles Bibliográficos
Publicado en:Front Mol Neurosci
Main Authors: Govindarajulu, Manoj, Pinky, Priyanka D., Steinke, Ian, Bloemer, Jenna, Ramesh, Sindhu, Kariharan, Thiruchelvan, Rella, Robert T., Bhattacharya, Subhrajit, Dhanasekaran, Muralikrishnan, Suppiramaniam, Vishnu, Amin, Rajesh H.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Neuroscience
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7437142/
https://ncbi.nlm.nih.gov/pubmed/32903435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2020.00138
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