Gut Metabolite TMAO Induces Synaptic Plasticity Deficits by Promoting Endoplasmic Reticulum Stress

Dysbiosis of gut microbiota is strongly associated with metabolic diseases including diabetes mellitus, obesity, and cardiovascular disease. Recent studies indicate that Trimethylamine N-oxide (TMAO), a gut microbe-dependent metabolite is implicated in the development of age-related cognitive declin...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Mol Neurosci
Main Authors: Govindarajulu, Manoj, Pinky, Priyanka D., Steinke, Ian, Bloemer, Jenna, Ramesh, Sindhu, Kariharan, Thiruchelvan, Rella, Robert T., Bhattacharya, Subhrajit, Dhanasekaran, Muralikrishnan, Suppiramaniam, Vishnu, Amin, Rajesh H.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Neuroscience
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7437142/
https://ncbi.nlm.nih.gov/pubmed/32903435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2020.00138
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