Gut Metabolite TMAO Induces Synaptic Plasticity Deficits by Promoting Endoplasmic Reticulum Stress

Dysbiosis of gut microbiota is strongly associated with metabolic diseases including diabetes mellitus, obesity, and cardiovascular disease. Recent studies indicate that Trimethylamine N-oxide (TMAO), a gut microbe-dependent metabolite is implicated in the development of age-related cognitive declin...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Govindarajulu, Manoj, Pinky, Priyanka D., Steinke, Ian, Bloemer, Jenna, Ramesh, Sindhu, Kariharan, Thiruchelvan, Rella, Robert T., Bhattacharya, Subhrajit, Dhanasekaran, Muralikrishnan, Suppiramaniam, Vishnu, Amin, Rajesh H.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7437142/
https://ncbi.nlm.nih.gov/pubmed/32903435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2020.00138
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