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HFIP-Promoted Synthesis of Substituted Tetrahydrofurans by Reaction of Epoxides with Electron-Rich Alkenes

In the present work, the employment of fluorinated alcohols, specifically 1,1,1,3,3,3-hexafluoroisopropanol (HFIP), as solvent and promoter of the catalyst-free synthesis of substituted tetrahydrofuranes through the addition of electron-rich alkenes to epoxydes is described. The unique properties of...

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Publicat a:Molecules
Autors principals: Llopis, Natalia, Baeza, Alejandro
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7435839/
https://ncbi.nlm.nih.gov/pubmed/32751509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25153464
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