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Formal [3+2] Cycloaddition Reactions of Electron-Rich Aryl Epoxides with Alkenes under Lewis Acid Catalysis Affording Tetrasubstituted Tetrahydrofurans

We report on the regio- and stereoselective synthesis of tetrahydrofurans by reaction between epoxides and alkenes in the presence of a Lewis acid. This is an unprecedented formal [3+2] cycloaddition reaction between an epoxide and an alkene. The chemical reaction represents a very concise synthesis...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Macías-Villamizar, Víctor E., Cuca-Suárez, Luís, Rodríguez, Santiago, González, Florenci V.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7036929/
https://ncbi.nlm.nih.gov/pubmed/32041165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25030692
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