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Immunotoxins with decreased immunogenicity and improved activity
Recombinant immunotoxins, containing an Fv fragment and a bacterial toxin, frequently elicit neutralizing antibodies, nearly always against the toxin. Moxetumomab pasudotox (previously called CAT-8015 or HA22) contains an anti-CD22 Fv fused to PE38, a truncated form of Pseudomonas exotoxin, containi...
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| Publicado no: | Leuk Lymphoma |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7435130/ https://ncbi.nlm.nih.gov/pubmed/21504287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2011.573039 |
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