A TOMM40/APOE allele encoding APOE‐E3 predicts high likelihood of late‐onset Alzheimer’s disease in autopsy cases

BACKGROUND: The APOE‐ε4 allele is an established risk factor for Alzheimer's disease (AD). TOMM40 located adjacent to APOE has also been implicated in AD but reports of TOMM40 associations with AD that are independent of APOE‐ε4 are at variance. METHODS: We investigated associations of AD with...

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Bibliographic Details
Published in:Mol Genet Genomic Med
Main Authors: Soyal, Selma M., Kwik, Markus, Kalev, Ognian, Lenz, Stefan, Zara, Greta, Strasser, Peter, Patsch, Wolfgang, Weis, Serge
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7434743/
https://ncbi.nlm.nih.gov/pubmed/32472747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.1317
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