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A TOMM40/APOE allele encoding APOE‐E3 predicts high likelihood of late‐onset Alzheimer’s disease in autopsy cases

BACKGROUND: The APOE‐ε4 allele is an established risk factor for Alzheimer's disease (AD). TOMM40 located adjacent to APOE has also been implicated in AD but reports of TOMM40 associations with AD that are independent of APOE‐ε4 are at variance. METHODS: We investigated associations of AD with...

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Detalhes bibliográficos
Publicado no:Mol Genet Genomic Med
Main Authors: Soyal, Selma M., Kwik, Markus, Kalev, Ognian, Lenz, Stefan, Zara, Greta, Strasser, Peter, Patsch, Wolfgang, Weis, Serge
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7434743/
https://ncbi.nlm.nih.gov/pubmed/32472747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.1317
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