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Spatial Distribution Profiles of Emtricitabine, Tenofovir, Efavirenz, and Rilpivirine in Murine Tissues Following In Vivo Dosing Correlate with Their Safety Profiles in Humans
[Image: see text] Emtricitabine (FTC), tenofovir (TFV), efavirenz (EFV), and rilpivirine (RPV) are currently used as components of HIV combination therapy. Although these drugs are widely used in antiretroviral therapy, several organ toxicities related to TFV and EFV have been observed clinically. T...
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| Published in: | ACS Pharmacol Transl Sci |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American
Chemical Society
2020
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7433710/ https://ncbi.nlm.nih.gov/pubmed/32832868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.0c00015 |
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