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Necdin regulates BMAL1 stability and circadian clock through SGT1-HSP90 chaperone machinery

Circadian clocks are endogenous oscillators that control ∼24-hour physiology and behaviors in virtually all organisms. The circadian oscillator comprises interconnected transcriptional and translational feedback loops, but also requires finely coordinated protein homeostasis including protein degrad...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Lu, Renbin, Dong, Yufan, Li, Jia-Da
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7430654/
https://ncbi.nlm.nih.gov/pubmed/32667666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa601
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