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Sgt1, a co-chaperone of Hsp90 stabilizes Polo and is required for centrosome organization

Sgt1 was described previously in yeast and humans to be a Hsp90 co-chaperone and required for kinetochore assembly. We have identified a mutant allele of Sgt1 in Drosophila and characterized its function. Mutations in sgt1 do not affect overall kinetochore assembly or spindle assembly checkpoint. sg...

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Detalhes bibliográficos
Main Authors: Martins, Torcato, Maia, André F, Steffensen, Soren, Sunkel, Claudio E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637337/
https://ncbi.nlm.nih.gov/pubmed/19131964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.283
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