Replicative aging is associated with loss of genetic heterogeneity from extrachromosomal circular DNA in Saccharomyces cerevisiae

Circular DNA can arise from all parts of eukaryotic chromosomes. In yeast, circular ribosomal DNA (rDNA) accumulates dramatically as cells age, however little is known about the accumulation of other chromosome-derived circles or the contribution of such circles to genetic variation in aged cells. W...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Prada-Luengo, Iñigo, Møller, Henrik D, Henriksen, Rasmus A, Gao, Qian, Larsen, Camilla Eggert, Alizadeh, Sefa, Maretty, Lasse, Houseley, Jonathan, Regenberg, Birgitte
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2020
Gaiak:
Genomics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7430651/
https://ncbi.nlm.nih.gov/pubmed/32609810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa545
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak