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Sensitive detection of circular DNAs at single-nucleotide resolution using guided realignment of partially aligned reads
BACKGROUND: Circular DNA has recently been identified across different species including human normal and cancerous tissue, but short-read mappers are unable to align many of the reads crossing circle junctions hence limiting their detection from short-read sequencing data. RESULTS: Here, we propose...
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| Publicat a: | BMC Bioinformatics |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6909605/ https://ncbi.nlm.nih.gov/pubmed/31830908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-3160-3 |
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