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Ureidothiophene inhibits interaction of bacterial RNA polymerase with –10 promotor element
Bacterial RNA polymerase is a potent target for antibiotics, which utilize a plethora of different modes of action, some of which are still not fully understood. Ureidothiophene (Urd) was found in a screen of a library of chemical compounds for ability to inhibit bacterial transcription. The mechani...
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| Publicat a: | Nucleic Acids Res |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7430646/ https://ncbi.nlm.nih.gov/pubmed/32652039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa591 |
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