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Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase
A combined structural, functional, and genetic approach was used to investigate inhibition of bacterial RNA polymerase (RNAP) by sorangicin (Sor), a macrolide polyether antibiotic. Sor lacks chemical and structural similarity to the ansamycin rifampicin (Rif), an RNAP inhibitor widely used to treat...
Tallennettuna:
| Päätekijät: | , , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2005
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC549610/ https://ncbi.nlm.nih.gov/pubmed/15692574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600499 |
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